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Beyond cholesterol: particle size and number matter more
What Gabriel reads for
LDL particle number (LDL-P) via NMR or Ion Mobility
LDL particle size (small vs. large)
HDL particle number and size

Cost
$100–$300
Turnaround
3–5 business days
Ordering path
LabCorp (NMR LipoProfile)
Results flow
Upload + interpret in Gabriel
What this test reveals
Advanced lipid testing goes far beyond standard cholesterol panels, measuring LDL particle number (LDL-P), particle size, Lp(a), ApoB, and inflammatory markers — the metrics that actually predict cardiovascular risk.
Your total cholesterol and LDL-C (standard cholesterol test) are poor predictors of heart attack risk. Particle number and size tell the real story: small, dense LDL particles are atherogenic; large, fluffy ones are benign. Two people with identical LDL-C can have vastly different cardiovascular risk based on particle characteristics.
People usually reach for this kind of diagnostic when they want a clearer read on ldl particle number (ldl-p) via nmr or ion mobility, ldl particle size (small vs. large), hdl particle number and size, especially when symptoms or prior testing still leave blind spots.
Once results are back, you can upload them into Gabriel to connect the findings to symptoms, protocols, and next-step testing instead of leaving them as a static report.
Commonly relevant for: Heart Disease Prevention, Weight Management Metabolic Health, Diabetes Blood Sugar.
Gabriel difference
Conventional lipid panels are dangerously outdated. A patient with 'normal' LDL cholesterol can have sky-high LDL particle number and be at serious cardiovascular risk — yet their doctor tells them they're fine. Advanced lipid testing reveals the truth. Gabriel uses particle number, Lp(a), and ApoB to assess true cardiovascular risk and to guide targeted interventions: omega-3s for particle size, niacin for Lp(a), bergamot for particle number — precision cardiology, not statin roulette.
Gabriel interprets results through a functional, root-cause lens: optimal ranges, pattern recognition across multiple diagnostics, and what the findings actually mean for action rather than just classification.
That means this test can feed directly into protocols, practitioner matching, food strategy, and follow-up testing instead of ending as a one-off PDF or lab portal result.
What to expect
01
Order
Order directly through LabCorp (NMR LipoProfile) or ask Gabriel whether there is a better path first.
02
Complete
A standard blood draw at a local lab, fasting for 10–12 hours before the test. Results arrive in 3–5 business days with detailed particle analysis.
03
Interpret
Upload the results to Gabriel for pattern recognition, protocol suggestions, and next-step guidance.
Frequently asked questions
Standard lipid panels measure total cholesterol, LDL, HDL, and triglycerides. Advanced panels add LDL particle number (LDL-P), LDL particle size, Lp(a), ApoB, ApoA1, and oxidized LDL. LDL particle number is a far better predictor of cardiovascular risk than LDL cholesterol alone.
Lipoprotein(a) is a genetically determined cardiovascular risk factor that standard tests don't measure. Elevated Lp(a) increases heart attack and stroke risk 2-3x. About 20% of people have elevated levels. It's largely genetic and doesn't respond to diet or exercise, but knowing your level changes how aggressively other risk factors should be managed.
Apolipoprotein B is a protein found on every atherogenic (artery-clogging) particle. One ApoB per particle means ApoB count equals your total atherogenic particle count. Many cardiologists now consider ApoB the single best lipid marker for cardiovascular risk assessment.
NMR LipoProfile or Cardio IQ panels cost $50-150 through direct labs. Insurance often covers them with documented cardiovascular risk factors. Cleveland HeartLab and Quest offer comprehensive panels. Testing every 6-12 months is standard for monitoring.
Tell Gabriel your symptoms, goals, and what you have already tried. You will get a more useful answer than a generic test catalog can give you.