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Recommended TestMetabolic HealthUpload compatible
Advanced Cardiovascular Risk Panel
Inflammation and clotting markers that predict heart attack risk
$200–$4003–5 business days3 ordering options
What Gabriel reads for
High-sensitivity C-reactive protein (hsCRP — systemic inflammation)
Lipoprotein-associated phospholipase A2 (Lp-PLA2 — vascular inflammation)
Myeloperoxidase (MPO — plaque instability)
Cost
$200–$400
Turnaround
3–5 business days
Ordering path
Cleveland HeartLab
Results flow
Upload + interpret in Gabriel
What this test reveals
What this test reveals
Advanced cardiovascular risk testing goes beyond cholesterol to measure inflammatory markers (hsCRP, Lp-PLA2, MPO), clotting factors (fibrinogen, homocysteine), and vascular health markers (ADMA, TMAO) that drive atherosclerosis and thrombosis.
Cholesterol is a weak predictor of heart attack risk. Inflammation, endothelial dysfunction, and hypercoagulability are the real drivers. Half of all heart attacks occur in people with normal cholesterol. This panel reveals the hidden risk factors conventional cardiology ignores.
People usually reach for this kind of diagnostic when they want a clearer read on high-sensitivity c-reactive protein (hscrp — systemic inflammation), lipoprotein-associated phospholipase a2 (lp-pla2 — vascular inflammation), myeloperoxidase (mpo — plaque instability), especially when symptoms or prior testing still leave blind spots.
Once results are back, you can upload them into Gabriel to connect the findings to symptoms, protocols, and next-step testing instead of leaving them as a static report.
Commonly relevant for: Heart Disease Prevention, Diabetes Blood Sugar, Autoimmune Disorders.
Gabriel difference
Why this becomes more useful inside Gabriel
Heart disease is an inflammatory disease, not a cholesterol disease. A patient with low hsCRP and healthy endothelial function has low risk even with high cholesterol. Conversely, a patient with high hsCRP, elevated homocysteine, and sky-high Lp-PLA2 is at serious risk even with 'good' cholesterol. Gabriel uses cardiovascular risk markers to identify true risk and to design targeted anti-inflammatory, methylation-supporting, and endothelial-healing protocols that address root causes.
Gabriel interprets results through a functional, root-cause lens: optimal ranges, pattern recognition across multiple diagnostics, and what the findings actually mean for action rather than just classification.
That means this test can feed directly into protocols, practitioner matching, food strategy, and follow-up testing instead of ending as a one-off PDF or lab portal result.
What to expect
What to expect from ordering to results
01
Order
Order directly through Cleveland HeartLab or ask Gabriel whether there is a better path first.
02
Complete
A fasting blood draw at a local lab. Fast for 10–12 hours (water only).
03
Interpret
Upload the results to Gabriel for pattern recognition, protocol suggestions, and next-step guidance.
Frequently asked questions
Questions people usually ask before ordering
Beyond standard lipids, it typically measures hs-CRP, homocysteine, Lp(a), ApoB, fibrinogen, insulin, HbA1c, and sometimes coronary calcium score or CIMT (carotid intima-media thickness). This comprehensive view catches risk factors that standard panels miss entirely.
Anyone with family history of heart disease, metabolic syndrome, diabetes, or high blood pressure. Also valuable for people whose standard cholesterol looks 'normal' but who have other risk factors. About 50% of heart attacks occur in people with 'normal' cholesterol.
A quick CT scan that measures calcified plaque in your coronary arteries. A score of zero is excellent. Above 100 indicates significant plaque. Above 400 is high risk. It's one of the best predictors of heart attack risk and costs $75-150 at most imaging centers, often without insurance.
Blood work portion typically $200-400. Coronary calcium CT adds $75-150. Insurance coverage varies; many markers are covered with appropriate diagnosis codes. Direct-to-consumer labs offer panels starting around $150.
Not sure which test belongs in your workup?
Tell Gabriel your symptoms, goals, and what you have already tried. You will get a more useful answer than a generic test catalog can give you.