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Emerging DiagnosticInfectious DiseaseUpload compatible
Comprehensive Lyme Disease Testing
Detect the great imitator that standard testing misses
$300–$700 (varies by panel comprehensiveness)10–14 business days3 ordering options
What Gabriel reads for
Borrelia burgdorferi antibodies (IgG and IgM)
Western blot band analysis (including Lyme-specific bands 23, 31, 34, 39, 83-93)
C6 peptide antibody (specific Lyme marker)
Cost
$300–$700 (varies by panel comprehensiveness)
Turnaround
10–14 business days
Ordering path
IGeneX
Results flow
Upload + interpret in Gabriel
What this test reveals
What this test reveals
Comprehensive Lyme disease testing uses advanced methods like Western blot IgG and IgM, C6 peptide, CD57, and co-infection panels to detect Borrelia burgdorferi and related tick-borne infections that standard ELISA screening completely misses.
Lyme disease is the most underdiagnosed infection in America. The standard two-tier CDC testing (ELISA + Western blot) misses over 50% of Lyme cases. Specialty labs use more sensitive testing criteria and check for co-infections like Babesia, Bartonella, Ehrlichia, and Anaplasma that often accompany Lyme and drive additional symptoms.
People usually reach for this kind of diagnostic when they want a clearer read on borrelia burgdorferi antibodies (igg and igm), western blot band analysis (including lyme-specific bands 23, 31, 34, 39, 83-93), c6 peptide antibody (specific lyme marker), especially when symptoms or prior testing still leave blind spots.
Once results are back, you can upload them into Gabriel to connect the findings to symptoms, protocols, and next-step testing instead of leaving them as a static report.
Commonly relevant for: Lyme Disease, Chronic Fatigue Fibromyalgia, Autoimmune Disorders.
Gabriel difference
Why this becomes more useful inside Gabriel
Lyme disease is called 'the great imitator' because it mimics chronic fatigue, fibromyalgia, MS, arthritis, and psychiatric disorders. Conventional testing is notoriously unreliable, leaving patients suffering for years without a diagnosis. Gabriel uses specialty lab testing with more sensitive criteria to catch Lyme and co-infections that standard testing misses — then designs comprehensive protocols combining antimicrobial herbs, immune support, biofilm disruptors, and detoxification to address the infection and its downstream effects.
Gabriel interprets results through a functional, root-cause lens: optimal ranges, pattern recognition across multiple diagnostics, and what the findings actually mean for action rather than just classification.
That means this test can feed directly into protocols, practitioner matching, food strategy, and follow-up testing instead of ending as a one-off PDF or lab portal result.
What to expect
What to expect from ordering to results
01
Order
Order directly through IGeneX or ask Gabriel whether there is a better path first.
02
Complete
A blood draw at a specialty lab or using an at-home kit. The sample is analyzed using more sensitive testing methods than standard CDC criteria.
03
Interpret
Upload the results to Gabriel for pattern recognition, protocol suggestions, and next-step guidance.
Frequently asked questions
Questions people usually ask before ordering
Standard two-tier testing (ELISA followed by Western blot) misses up to 50% of cases, especially in early infection or chronic Lyme. The tests detect antibodies, not the organism itself, and the immune response can be blunted or delayed. Many people with clinical Lyme have negative standard tests.
Specialty labs like IGeneX and Vibrant Wellness offer expanded Western blot panels, PCR (direct DNA detection), and immunofluorescence. iSpot Lyme measures T-cell response rather than antibodies. These catch cases that standard testing misses, especially for co-infections like Babesia, Bartonella, and Ehrlichia.
Ticks often carry multiple organisms. Common co-infections include Babesia (a malaria-like parasite), Bartonella (causes neurological and psychiatric symptoms), Ehrlichia/Anaplasma (affect white blood cells), and Mycoplasma. Co-infections often explain why some Lyme patients don't respond to standard antibiotic protocols.
Standard two-tier testing costs $50-100 and is usually insurance-covered. Specialty testing through IGeneX or Vibrant Wellness costs $500-1,500 depending on the panel. Many Lyme-literate practitioners consider specialty testing essential for accurate diagnosis.
Not sure which test belongs in your workup?
Tell Gabriel your symptoms, goals, and what you have already tried. You will get a more useful answer than a generic test catalog can give you.