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Detect bacterial overgrowth that standard testing misses
What Gabriel reads for
Hydrogen gas production (hydrogen-producing bacteria)
Methane gas production (methanogenic archaea)
Hydrogen sulfide (H2S) if using a trio test

Cost
$200–$300
Turnaround
7–10 business days
Ordering path
Trio-Smart (trio test with H2S)
Results flow
Upload + interpret in Gabriel
What this test reveals
The Small Intestinal Bacterial Overgrowth (SIBO) breath test measures hydrogen and methane gas production after ingesting a lactulose or glucose solution, revealing bacterial overgrowth in your small intestine — a condition that drives bloating, gas, diarrhea, and malabsorption.
SIBO is wildly underdiagnosed yet affects an estimated 60–80% of IBS patients. Standard stool tests can't detect it because they only sample the large intestine. Breath testing is the gold standard for SIBO diagnosis.
People usually reach for this kind of diagnostic when they want a clearer read on hydrogen gas production (hydrogen-producing bacteria), methane gas production (methanogenic archaea), hydrogen sulfide (h2s) if using a trio test, especially when symptoms or prior testing still leave blind spots.
Once results are back, you can upload them into Gabriel to connect the findings to symptoms, protocols, and next-step testing instead of leaving them as a static report.
Commonly relevant for: Gut Issues Ibs Sibo Leaky Gut, Malabsorption, Chronic Fatigue Fibromyalgia.
Gabriel difference
SIBO is the hidden driver behind countless 'IBS' diagnoses. Patients suffer for years on restrictive diets without addressing the root cause: bacteria in the wrong place, fermenting food in your small intestine and creating gas, inflammation, and malabsorption. Gabriel uses SIBO breath test results to design targeted antimicrobial protocols (herbal or pharmaceutical), prokinetic support, and dietary strategies that actually resolve the overgrowth instead of just managing symptoms.
Gabriel interprets results through a functional, root-cause lens: optimal ranges, pattern recognition across multiple diagnostics, and what the findings actually mean for action rather than just classification.
That means this test can feed directly into protocols, practitioner matching, food strategy, and follow-up testing instead of ending as a one-off PDF or lab portal result.
What to expect
01
Order
Order directly through Trio-Smart (trio test with H2S) or ask Gabriel whether there is a better path first.
02
Complete
You'll fast overnight, then drink a lactulose or glucose solution and breathe into collection tubes every 15–20 minutes for 3 hours. The test is done entirely at home.
03
Interpret
Upload the results to Gabriel for pattern recognition, protocol suggestions, and next-step guidance.
Frequently asked questions
Small Intestinal Bacterial Overgrowth (SIBO) occurs when bacteria that normally live in the large intestine colonize the small intestine. This causes fermentation of food in the wrong place, leading to bloating, gas, abdominal pain, diarrhea or constipation, and nutrient malabsorption.
You drink a sugar solution (lactulose or glucose) and blow into collection tubes at timed intervals over 2-3 hours. Bacteria in the small intestine ferment the sugar and produce hydrogen and/or methane gas, which is absorbed into your bloodstream and exhaled. Elevated gas levels at specific time points indicate SIBO.
Hydrogen-dominant SIBO typically causes diarrhea. Methane-dominant SIBO (now called IMO, Intestinal Methanogen Overgrowth) typically causes constipation. Some people have both. A newer marker, hydrogen sulfide, is associated with diarrhea and sulfur-smelling gas. Treatment protocols differ for each type.
Sensitivity ranges from 60-80% depending on the substrate used. Glucose tests are more specific but only detect overgrowth in the upper small intestine. Lactulose tests cover more territory but have more false positives. Despite limitations, the breath test remains the standard non-invasive SIBO assessment.
Typically $150-250 for at-home collection kits. Labs like Aerodiagnostics, Commonwealth, and Genova offer them. Some gastroenterologists perform in-office testing. Insurance may cover it with a GI referral.
Tell Gabriel your symptoms, goals, and what you have already tried. You will get a more useful answer than a generic test catalog can give you.